KMID : 0356620130280030226
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Journal of Korean Society of Endocrinology 2013 Volume.28 No. 3 p.226 ~ p.230
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Graves¡¯ Disease that Developed Shortly after Surgery for Thyroid Cancer
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Yu Hea-Min
Park Soon-Hyun Lee Jae-Min Park Kang-Seo
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Abstract
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Graves¡¯ disease is an autoimmune disorder that may present with various clinical manifestations of hyperthyroidism. Patients with Graves¡¯ disease have a greater number of thyroid nodules and a higher incidence of thyroid cancer compared with patients with normal thyroid activity. However, cases in which patients are diagnosed with recurrence of Graves¡¯ disease shortly after partial thyroidectomy for thyroid cancer are very rare. Here we report a case of hyperthyroid Graves¡¯ disease that occurred after partial thyroidectomy for papillary thyroid cancer. In this case, the patient developed hyperthyroidism 9 months after right hemithyroidectomy, and antithyroglobulin autoantibody and thyroid stimulating hormone receptor stimulating autoantibody were positive. Therefore, we diagnosed Graves¡¯ disease on the basis of the laboratory test results and thyroid ultrasonography findings. The patient was treated with and maintained on antithyroid drugs. The mechanism of the recurrence of Graves¡¯ disease in this patient is still unclear. The mechanism may have been the improper response of the immune system after partial thyroidectomy. To precisely determine the mechanisms in Graves¡¯ disease after partial thyroidectomy, further studies based on a greater number of cases are needed.
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KEYWORD
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Graves¡¯ disease, Partial thyroidectomy, Thyroid cancer, papillary
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